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(* Corresponding Author; # equal contribution)

  • »»» Mitochondrial stress and aging: Lessons from C. elegans.【PDF】

    Chen P, Zhang LY, Chen D*, Tian Y*
    Seminars in Cell and Developmental Biology, 2023, 154(Pt A):69-76.

  • »»» 跨组织线粒体应激信号交流调控机体衰老的研究进展.【PDF】

    张茜#, 王子豪#, 田烨*
    遗传, 2023, 45(3):187-197.

  • »»» Inter-tissue Communication of Mitochondrial Stress and Metabolic Health.【PDF】

    Zhang HL#, Li XY#, Fan WD#, Pandovski S#, Tian Y* and Dillin A*
    Life Metabolism, 2023, 2(1):1-11.

  • »»» Neuron-Periphery Mitochondrial Stress Communication in Aging and Diseases.【PDF】

    Li JS#, Cui JM# and Tian Y*
    Life Medicine, 2022, 1(2):168-178.

  • »»» Two Sensory Neurons Coordinate the Systemic Mitochondrial Stress Response via GPCR Signaling in C. elegans.【PDF】

    Liu YL#, Zhou J#, Zhang N, Wu XY, Zhang Q, Zhang WF, Li XY and Tian Y*
    Developmental Cell, 2022, 57(21):2469-2482.e5.

  • »»» The Landscape of Aging.【PDF】

    Cai YS#, Song W#, Li JM#, Jing Y#, Liang CQ#, Zhang LY#, Zhang X#, Zhang WH#, Liu BB#, An YP#, Li JY#, Tang BX#, SY#, Wu XY#, Liu YX#, Zhuang CL#, Ying YL#, Dou XF#, Chen Y#, Xiao FH#, Li DF#, Yang RC#, Zhao Y#, Wang Y#, Wang LH#, Li YJ#, Ma S*, Wang S*, Song XY*, Ren J*, Zhang L*, Wang J*, Zhang WQ*, Xie ZW*, Qu J*, Wang JW*, Xiao YC*, Tian Y*, Wang GL*, Hu P*, Ye J*, Sun Y*, Mao ZY*, Kong QP* and et al
    Science China-Life Sciences, 2022, 65(12):2354-2454.

  • »»» Protein Disulfide Isomerase PDI-6 Assists Wnt Secretion to Coordinate Inter-tissue UPRmt and Lifespan.【PDF】

    Li XY, Li JS, Zhu D, Zhang N, Hao XS, Zhang WF, Zhang Q, Liu YL, Wu XY and Tian Y*
    Cell Reports, 2022, 39(10):110931.

  • »»» Mitochondrial-to-nuclear Communication in Aging: An Epigenetic Perspective.【PDF】

    Zhu D#, Li XY#, Tian Y*
    Trends in Biochemical Sciences, 2022, 47(8):645-659.

  • »»» Molecular Insights into the Transgenerational Inheritance of Stress Memory.【PDF】

    Zhang Q, Tian Y*
    Journal of Genetics and Genomics, 2022, 49(2):89-95.

  • »»» The Memory of Neuronal Mitochondrial Stress is Inherited Transgenerationally via Elevated mtDNA Levels.【PDF】

    Zhang Q, Wang ZH, Zhang WF, Wen QB, Li XY, Zhou J, Wu XY, Guo YQ, Liu YL, Wei CS, Qian WF, Tian Y*
    Nature Cell Biology, 2021, 23(8):870-880.

  • »»» The RNA Helicase Dhx15 Mediates Wnt-Induced Antimicrobial Protein Expression in Paneth Cells.【PDF】

    Wang YL#, He KX#, Sheng BF#, Lei XQ, Tao WY, Zhu XL, Wei Z, Fu RJ, Wang AL, Bai SD, Zhang Z, Hong N, Ye C, Tian Y, Wang J, Li MS, Zhang KG, Li L, Yang H*, Li HB*, Flavell RA*, Zhu S*
    PNAS, 2021, 118(4):e2017432118.

  • »»» Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.【PDF】

    Rong BW#, Zhang Q#, Wan JK, Xing SH, Dai RF, Li Y, Cai JB, Xie JY, Song Y, Chen JW, Zhang L, Yan GQ, Zhang W, Gao H, Han JD, Qu QH, Ma HH*, Tian Y*, Lan F*
    Cell Reports, 2020, 33(12):108544.

  • »»» NuRD Mediates Mitochondrial Stress-Induced Longevity via Chromatin Remodeling in Response to Acetyl-CoA Level.【PDF】

    Zhu D#, Wu XY#, Zhou J, Li XY, Huang XH, Li JS, Wu JB, Bian Q, Wang YC and Tian Y*
    Science Advances, 2020, 6(31):eabb2529.

  • »»» The Mitochondrial unfolded protein response is mediated cell-non-autonomously by retromer-dependent Wnt signaling.【PDF】

    Zhang Q#, Wu XY#, Chen P#, Liu LM, Xin N, Tian Y*, and Dillin A*
    Cell, 2018, 174(4):870-883.

  • »»» Mitochondrial stress induces chromatin reorganization to promote longevity and UPRmt.【PDF】

    Tian Y, Garcia G, Bian Q, Steffen K, Joe Larry, Wolff S, Meyer BJ, and Dillin A*
    Cell, 2016, 165(5):1197-1208.

  • »»» Mitochondrial UPR: A double-edged sword.【PDF】

    Tian Y#, Merkwirth C#, and Dillin A*
    Trends in Cell Biology, 2016, 26(8):563-565.

  • »»» Neuroendocrine coordination of mitochondrial stress signaling and proteostasis.【PDF】

    Berendzen K#, Durieux J#, Shao LW, Tian Y, Kim H, Wolff S, Liu Y, and Dillin A*
    Cell, 2016, 166(6):1553-1563.

  • »»» ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.【PDF】

    Russell RC, Tian Y, Yuan H, Park HW, Chang YY, Kim J, Kim H, Neufeld TP, Dillin A, and Guan KL*
    Nature Cell Biology, 2013, 15(7):741-750.

  • »»» C. elegans screen identifies autophagy genes specific to multicellular organisms.【PDF】

    Tian Y#, Li Z#, Hu W#, Ren H#, Tian E, Zhao Y, Lu Q, Huang X, Yang P, Li X, Wang X, Kovacs A, Yu L*, and Zhang H*
    Cell, 2010, 141(6):1042-1055.

  • »»» Four metazoan autophagy genes regulate cargo recognition, autophagosome formation and autolysosomal degradation.【PDF】

    Tian Y, Ren H, Zhao Y, Lu Q, Huang X, Yang P, and Zhang H*
    Autophagy, 2010, 6(7):984-985.

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